DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2011; 136(46): 2378-2381DOI: 10.1055/s-0031-1292057 Kommentar | CommentaryHypertensiologie, Pharmakotherapie© Georg Thieme Verlag KG Stuttgart · New YorkZum Stellenwert der Diuretika bei der HypertoniebehandlungR. Düsing1 1Medizinische Klinik und Poliklinik 1, Universität Bonn Recommend Article Abstract Buy Article Schlüsselwörter Diuretika - Thiazide - Thiazid-artige Diuretika - JNC - ESC/ESH - BHS - NICE Keywords diuretics - thiazides - thiazid-like diuretics - JNC - ESC/ESH - BHS - NICE Full Text References Literatur 1 Burke T A, Sturkenboom M C, Lu S E. et al . Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice. J Hypertens. 2006; 24 1193-1200 2 Chobanian A V, Bakris G L, Black H R. et al . Report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. JAMA. 2003; 289 2560-2572 3 Corrao G, Zambon A, Parodi A. et al . Discontinuation of and changes in drug therapy for hypertension among newly-treated patients: a population-based study in Italy. J Hypertens. 2008; 26 819-824 4 Dahlof B, Sever P S, Poulter N R. et al, ASCOT Investigators . Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet. 2005; 366 895-906 5 Davis B R, Cutler J A, Furberg C D. et al . Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Ann Intern Med. 2002; 137 313-320 6 Düsing R. Alte oder neue Antihypertensiva? Konsequenzen aus „ALLHAT“. Dtsch Med Wochenschr. 2003; 128 214-216 7 Düsing R. Diuretika, Pharmakologie und therapeutischer Einsatz. Medizinisch-pharmakologisches Kompendium,. Stuttgart: Wissenschaftliche Verlagsgesellschaft mbH; 1986 ISBN 3–8047–0754–8 8 Düsing R. Optimizing blood pressure control through the use of fixed combinations. Vasc Health Risk Manag. 2010; 6 321-325 9 Düsing R. Therapie der Hypertonie mit Diuretika: Wirksamkeit, Sicherheit und Verträglichkeit. Internist. 2011; DOI: 10.1007/s00108–011–2915–3 10 Ernst M, Moser M. Use of diuretics in patients with hypertension. N Engl J Med. 2009; 361 2153-2164 11 Guidelines Committee . 2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens. 2003; 21 1011-1053 12 Hypertension Detection and Follow-up Program Cooperative Group . Five-year findings of the hypertension detection and follow-up program. I. Reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA. 1979; 242 2562-2571 13 Jamerson K, Weber M A, Bakris G L. et al . Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med. 2008; 359 2417-2428 14 Mancia G, Laurent S, Agabiti-Rosei E. et al . Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens. 2009; 27 2121-2158 15 Messerli F H, Makani H, Benjo A. et al . Antihypertensive efficacy of hydrochlorothiazide as evaluated by ambulatory blood pressure monitoring. J Am Coll Cardiol. 2011; 57 590-600 16 Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. A cooperative study. JAMA. 1977; 237 255-261 17 SHEP Cooperative Research Group . Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 1991; 265 3255-3264 18 The 1980 report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1980; 140 1280-1285 19 The 1984 Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1984; 144 1045-1057 20 The 1988 report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1988; 148 1023-1038 21 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group . Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting-enzyme inhibitor or calcium channel blocker vs. diuretic. JAMA. 2002; 288 2981-2997 22 The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group . Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). JAMA. 2000; 283 1967-1975 23 The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC V). Arch Intern Med. 1993; 153 154-183 24 The sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1997; 157 2413-2446 25 The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). 2007 Guidelines for the Management of Arterial Hypertension. J Hypertens. 2007; 25 1105-1187 26 VA Cooperative Study Group . Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg. JAMA. 1967; 202 1028-1034 27 VA Cooperative Study Group . Effects of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mm Hg. JAMA. 1970; 213 1143-1152 28 Wald D S, Law M, Morris J K. et al . Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med. 2009; 122 290-300 29 Williams B, Poulter N R, Brown M J, Davis M, McInnes G T, Potter J F, Sever P S, Thom S McG. Guidelines for management of hypertension: report of the fourth working party of the British Hypertension Society, 2004-BHS IV. Journal of Human Hypertension. 2004; 18 139-185 30 http://www.nice.org.uk/guidance/CG34 31 Partial update of Clinical Guideline 18 and 34 „Hypertension: The clinical management of primary hypertension in adults. Clinical Guideline. Methods, evidence and recommendations, May 2011. http://www.nice.org.uk Prof. Dr. med. Rainer Düsing Medizinische Klinik und Poliklinik 1 Wilhelmstr. 35–37 53111 Bonn Phone: 0228/287-22343 Fax: 0228/287-22593 Email: duesing@uni-bonn.de